Seroprevalence of human T cell lymphotropic virus infection and associated factors of risk in blood donors of Rio Branco city, AC, Brazil (1998-2001)

Revista da Sociedade Brasileira de Medicina Tropical

Alcântara, Luiz Carlos Júnior¹  Uchôa, Rita¹  Universidade Federal da Bahia, Salvador, Brasil¹  Fundação Oswaldo Cruz, Salvador, Brasil¹  Centro de Hematologia e Hemoterapia do Estado do Acre, Rio Branco, Brasil¹  Colin, Denise Duizit¹  Fundação para o Desenvolvimento das Ciências, Salvador, Brasil¹  Santos, Fred Luciano Neves¹  Fundação Hospital Estadual do Acre, Acre, Brasil¹  Tavares-Neto, José¹ 

关键词: HTLV-I/II;    Blood donors;    Prevalence;    Acre;    Western Amazon;   

DOI  :  10.1590/S0037-86822003000600006

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Between December 1998 and March 2001, for each HTLV-I/II seropositive blood donor (ELISA, Abbott®), two HTLV-I/II seronegative blood donors were also chosen. The blood samples were re-tested by ELISA (Murex®), and those seropositives were also tested by western blot and PCR. Of the 11,121 blood samples, 73 (0.66%) were positives (Abbott®), but only 12 (0.11%) remained positives (Murex®), whereas the 146 seronegatives were confirmed, even though the concordance index between these two ELISA tests was hopeless. The Western Blot confirmed the twelve blood samples as seropositives: 8 (0.07%) HTLV-I; two (0.02%) HTLV-II and two (0.02%) indeterminate, being by PCR, one HTLV-I and the other HTLV-II. Concluding, in this Western Amazon population the HTLV-I/II seroprevalence was too low, in spite of the greater prevalence of HTLV-II expected due to a great indigenous racial mixture.

【 授权许可】

Unknown