Revista da Sociedade Brasileira de Medicina Tropical | |
Antifungal activity of Caryocar brasiliensis (Caryocaraceae) against Cryptococcus neoformans | |
Ferri, Pedro Henrique1  Silva, Maria do Rosário Rodrigues1  Santos, Suzana da Costa1  Fernandes, Orionalda de Fátima Lisboa1  Universidade Federal de Goiás, Goiânia1  Paula, Thaliana de Freitas1  Garcia, Ana Cristina Ferreira1  Passos, Xisto Sena1  | |
关键词: Caryocar brasiliensis; Cerrado plant; Cryptococcus neoformans; Antifungal activity; | |
DOI : 10.1590/S0037-86822002000600013 | |
学科分类:农业科学(综合) | |
来源: Sociedade Brasileira de Medicina Tropical | |
【 摘 要 】
The widespread occurrence of cryptococcosis mainly in immunocompromised patients and the side effects of available drugs which are effective against this mycosis have led investigators to search for new antimycotic agents. Caryocar brasiliensis derived compounds were investigated against Cryptococcus neoformans using the agar dilution method. Based on MIC values, the best results were obtained with a concentration of £ 250µg/mL of cuticular waxes of the Caryocar brasiliensis leaf collected during the dry period (170.8mm of precipitation) which inhibited the growth of 91.3% (21/23) Cryptococcus neoformans isolates.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912010166138ZK.pdf | 340KB | download |