Hepatitis E

Revista da Sociedade Brasileira de Medicina Tropical

Hospital General de Agudos Ramos Mejia, Buenos Aires, Argentina¹  Schinoni, Maria Isabel¹  Paraná, Raymundo¹ 

关键词: Hepatitis E;    Liver failure;    Pregnancy;    Virus;   

DOI  :  10.1590/S0037-86822002000300009

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Hepatitis E virus (HEV) is the second most frequent hepatotropic virus transmitted via fecal-oral route, following closely behind hepatitis A virus. The great epidemics of hepatitis described during the 50s and 60s, in India, were caused by this virus. Epidemic bursts have also been described in Central Africa, Latin America, Middle East and in the independent Republics of the ex-Soviet Union. The clinical features of the disease do not differ from those reported for other viral hepatitides. There have been no cases of chronic hepatitis E reported. Around 20% of women infected during pregnancy develop a severe form of hepatitis which courses to liver failure. Diagnosis of hepatitis is confirmed when antibodies (using ELISA) of the IgM class (acute phase) and/or IgG (infected and cured) are found in the serum. Immunoblot and PCR-RNA may be used as necessary. There is no specific treatment for hepatitis E. Hyperimmune serum has been tried by some authors. Prevention is achieved by following the habitual hygienic and dietetic recommendations valid for diseases transmitted by contaminated water. There is no effective vaccine against the disease.

【 授权许可】

Unknown