An attempt of specific treatment by means of ticlopidine of patients with chronic phase of Chagas' disease

Revista da Sociedade Brasileira de Medicina Tropical

Ferriolli Filho, Francisco¹  Hospital São Salvador, Goiânia, Brasil¹  Amato, Valdir Sabbaga¹  Amato Neto, Vicente¹  Rassi, Anis¹  Rassi, Gustavo Gabriel¹ 

关键词: Chronic phase of Chagas' disease;    Ticlopidine;    Specific treatment;   

DOI  :  10.1590/S0037-86822000000200012

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

In a previous study, ticlopidine decreased the parasitemy and mortality of mice infected by Trypanosoma cruzi. Therefore, this drug was administered to 12 patients with Chagas' disease, in the chronic phase. For 90 days, 150, 200 or 250mg were utilized according to whether the recipients were children, adolescents or adults, respectively. A fully unsuccessful outcome was documented, both sorologically as well as parasitologically.

【 授权许可】

Unknown