Seroepidemiologic survey in São Luis Island, State of Maranhão, Brazil, during a dengue fever epidemics

Revista da Sociedade Brasileira de Medicina Tropical

Fundação Nacional de Saúde no Estado do Ceará, Fortaleza¹  Amorim, Sílvia M.C.¹  Rodrigues, Sueli G.¹  Fonseca, Niedja¹  Raposo, Maria L.¹  Rosa, Jorge F.S. Travassos da¹  Vasconcelos, Pedro Fernando da C.¹  Rosa, Amélia P.A. Travassos da¹  Fundação Nacional de Saúde no Estado do Maranhão, São Luís, Brasil¹  Rosa, Elizabeth S. Travassos da¹  Moura, Cleide M.P.¹  Lima, José W.O.¹  Instituto Evandro Chagas, Belém¹ 

关键词: Dengue fever;    Epidemic;    Epidemiology;    Serologic survey;    São Luis Island;    Maranhão State;    Brazil;   

DOI  :  10.1590/S0037-86821999000200009

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

The Island of São Luis in the State of Maranhão, constituted by the municipalities of São Luis - SL (835,428 inhabitants), São José de Ribamar - SJR (60,633 inhabitants) and Paço do Lumiar - PL (80,274 inhabitants), has been suffering dengue (DEN) fever epidemics since 1995, caused by DEN-1. In 1996, from August through October, an aleatory sero-epidemiologic survey was carried out in order to estimate the incidence of DEN infection and to analyze other clinical and epidemiological parameters. A questionnaire was applied and serum samples were simultaneously obtained. Serum samples were tested by hemagglutination inhibition (HI). Results were analyzed using Lotus123, Epi-info 6.0, Excel 5.0 and STATA softwares. A total of 1,217 serum samples were obtained (101 of PL, 100 of SJR and 1017 of SL). The rate of DEN was 55.4% in PL, 28% in SJR and 41.4% in SL, suggesting the occurrence of 401,933 infections. No difference was seen between males and females, but infection occurred more in the upper social class than in poor people (p < 0.003), and was more frequent in adults than in children (p < 0.0004). In SL, the incidence was stratified into seven sanitary districts (SD), and prevalence was found to range from 26.1% in SD4 to 56.8% in SD1 (p < 0.0001). Symptoms were more frequently reported by people whose HI was positive: they included fever, headache, chills, dizziness, retrobulbar pains, muscle and joint pains, nausea, anorexia and skin rash. In spite of the high incidence of infection, no hemorrhagic cases were reported.

【 授权许可】

Unknown