Renal anatomopathologic alterations in patients with acquired immunodeficiency syndrome

Revista da Sociedade Brasileira de Medicina Tropical

Faculdade de Medicina do Triângulo Mineiro, Uberaba¹  Pelá, Giovana Auad¹  Laguna-Torres, Victor Alberto¹  Menegaz, Renato Augusto¹  Prata, Aluízio¹  Reis, Marlene Antônia dos¹ 

关键词: Nefropathy - HIV;    AIDS;    Autopsy;    Immunossupression;   

DOI  :  10.1590/S0037-86821998000500007

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

Renal anatomopathological lesions were studied among 119 AIDS patients from Faculdade de Medicina do Triângulo Mineiro's University Hospital (Uberaba, MG, Brazil). From formalin-fixed blocks, slides were obtained and studied by light microscopy. Of 119 patients, 67 presented tubulointersticial nefritis (TIN), 18 inespecific, 2 xantogranulomatous and infections agents were found in 48 as follows: mycosis in 28 (16 Cryptococcus sp; 9 Histoplasma sp, 1 Candida sp e 2 Paracoccidioides brasiliensis), bacteria in 18 (9 Mycobacterium sp), virus in 6 (Citomegalovirus). Acute tubular necrosis was found in 43 cases (36.1%). Other diagnosis were: nefrocalcinosis (15.1%), arteriolar hyalinosis (22.7%), two cases of focal segmental glomerulosclerosis (1.7%) and one case of diffuse mesangial hyperplasia (0.8%). We conclude that the renal involvement in patients with AIDS, presents a wide spectrum of pathologies, secondary to complications related to oportunistic infections, therapeutic and diagnostic management, and the nefropathies associated to HIV.

【 授权许可】

Unknown