Tratamento da criptosporidiase, em pacientes com AIDS, por meio da paromomicina

Revista da Sociedade Brasileira de Medicina Tropical

Fernandes, Andreia Otaviani Di Pietro¹  Pôssa, Tamea Aparecida Linhares¹  Azevedo, Heber Dias¹  Levi, Guido Carlos¹  Silva, Nanei Ferreira¹  Stefani, Haydée Noleto Vasconcelos¹  Amato Neto, Vicente¹  Braz, Lúcia Maria Almeida¹  Mendonça, João Silva de¹ 

关键词: Ciyptosporidiasis;    AIDS;    Treatment;    Paromomycin;   

DOI  :  10.1590/S0037-86821996000400007

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

The authors treated with paromomycin 25 patients, with AIDS and cryptosporidiasis. The drug was given orally in a doses of 500mg qid, for a period of 14 days. Tolerance was good, with just two cases of mild side-effects. Clinical improvement was obtained in 19 (76%) patients. Parasitological cure, however, occurred only in a low percentage (25%). In some cases where initial success was observed, recrudescence occurred after some weeks or few months, but with retreatment again clinical improvement was obtained. Even if it does not lead to frequent parasite eradication, the good clinical results and tolerance permit us to consider paromomycin one of the few drugs effective for the treatment of cryptosporidial diarrhea in AIDS patients. Studies with maintainance therapy are indicated.

【 授权许可】

Unknown