Análise quantitativa de mastócitos e de granulócitos eosinófilos no miocárdio de ratos wistar cronicamente infectados pelo Trypanosoma cruzi. Contribuição ao conhecimento da fibrose miocárdia

Revista da Sociedade Brasileira de Medicina Tropical

Junqueira Júnior, Luiz Fernando¹  Beraldo, Paulo Sérgio Siebra¹  Lopes, Edison Reis¹  Pinheiro, Maria da Conceição Nascimento¹  Chapadeiro, Edmundo¹ 

关键词: Chagas'disease;    Myocardial fibrosis;    Mast cell;    Eosinophil granulocyte;   

DOI  :  10.1590/S0037-86821992000100007

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

We did mast cell and eosinophil granulocyte counts in the myocardium of forty chronic chagasic Wistar albino rats. We used 10 controls rats and 30 animals with late stage (8th month) infection of São Felipe, Y and Colombian Trypanosoma cruzi strains, with variable degree of chronic myocarditis. We found chronic fibrosing myocarditis (fibrosis) in 40% of the infected animals. It was detected increased mast cell count in the chagasic rats associated with infection and not related with myocardial fibrosis. There was no increase in the eosinophil counts.

【 授权许可】

Unknown