Histopatologia da hepatite de Lábrea

Revista da Sociedade Brasileira de Medicina Tropical

Andrade, Zilton A¹  Prata, Aluizio¹  Universidade de Brasília, Brasília¹  Universidade Federal do Amazonas, Manaus¹  UFBA, Salvador¹  Dourado, Heitor¹  Santos, João Barberino¹ 

关键词: Labrea hepatitis;    Hepatitis;    Histopathology;    Hepatic necrosis;   

DOI  :  10.1590/S0037-86821983000100005

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Medicina Tropical

【 摘 要 】

A histopathological study of the liver in seven fatal cases of Labrea hepatitis with different survival times permitted a sequential assessment of the changes. The fundamental earlier lesions were acute fatty change, lytic and coagulative necrosis of isolated cells in all the lobules, without massive or zona! necrosis. Mononuclear leucocytic infiltration in portal spaces, features of cholestasis, proliferation of small biliary ducts and liver-cell regeneration appeared as later consequences from the sudden acute parenchymal injury. The histologic picture is characteristic but not pathognomonic and gives no clues as to the pathogenesis of the disease, whifch remains idhiopathic. The tiver is the main and primary organ affected in this disease, changes in other organs being mild and secondary.

【 授权许可】

Unknown