Immunological Processes in Cancer: A Link Between Inflammation and Immunity | Science Publications

American Journal of Immunology

Anne Karine Martins Assunção¹  Isabela Casagrande Jeremias¹  Vanessa Jacob Victorino¹ 

关键词: Cancer;    Inflammation;    Immune Response;    Cancer Signaling;    Immunotherapy;   

DOI  :  10.3844/ajisp.2014.189.201

学科分类：过敏症与临床免疫学

来源: Science Publications

【 摘 要 】

Cancer is a worldwide issue and one of the most relevant death causes in child and adults. There are several causes that can lead to cancer development. It is well known that inflammation is one known hallmark of cancer and it favors tumor cells growth. Several alterations in immunological and inflammatory processes are caused in response to tumor presence and both innate and adaptive immunity have effective mechanism to destroy tumor cells. Nevertheless, distinct tumor types developed mechanisms to evade anti-tumor immunological responses. Here, we revise researches regarding inflammation and immune response during cancer development, as well as cancer signaling pathways and immunotherapy that have been performed in Brazil. The better understanding of the mechanisms regarding cancer and immunological processes is of huge importance and it may support the development of new cancer targets.

【 授权许可】

Unknown