PLACEBO-DRIVEN CLINICAL TRIALS OF TRANSFER POINT GLUCAN #300 IN CHILDREN WITH CHRONIC RESPIRATORY PROBLEMS: ANTIBODY PRODUCTION | Science Publications

American Journal of Immunology

Kral Vlastimil¹  Rajnohova Dobiasova Lucie¹  Richter Josef¹  Svozil Vladimir¹  Vetvicka Vaclav¹ 

关键词: Glucan;    Children;    Mucosal Immunity;    IgA;    IgM;    IgG;   

DOI  :  10.3844/ajisp.2013.43.47

学科分类：过敏症与临床免疫学

来源: Science Publications

【 摘 要 】

The role of glucan in stimulation of immune reactions has been well-established. In this report, we focused on the antibody production in glucan-supplemented children with chronic respiratory problems. We measured the levels of salivary IgA, IgM and IgG in 40 children aged 8-12 years and evaluated the effects of 100 mg d^-1 oral dose of glucan. We found a significant increase in production of all tested antibodies in the glucan-stimulated group, but a decrease of antibody production in the control group. A thirty-day oral application of yeast-based natural immunomodulator ?-glucan strongly stimulated the mucosal immunity of children with chronic respiratory problems.

【 授权许可】

Unknown