Novelty in Biomedicine | |
The Effects of Aerobic Exercise on NF-κB and TNF-α in Lung Tissue of Male Rat | |
Behzad Behzad Pakrad1  Hasan Asilian Mahabadi4  Sajad Rezaei1  Hamid Agha-Alinejad3  Batul Rezaei1  Mohamad Fashi2  | |
[1] Department of Physical Education & Sports Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran;Ph.D Candidate of Exercise Physiology, Department of Physical Education & Sports Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran.;Associate Professor of Exercise Physiology, Department of Physical Education & Sports Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran.;Associate Professor, Department of Occupational Health Engineering, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran. | |
关键词: aerobic exercise; inflammation; lung tissue; | |
DOI : | |
学科分类:生物科学(综合) | |
来源: Shahid Beheshti University of Medical Sciences | |
【 摘 要 】
Background: Regular aerobic exercise improves theBackground: Regular aerobic exercise improves the inflammatory status in different lung diseases. However, the effects of long-term aerobic exercise on the lung response have not been investigated. The present study evaluated the effect of aerobic exercise on the lung inflammatory. Materials and Methods:12 adult male Wistar rats were divided to 2 groups: A: control (n=6), B: aerobic exercise (five times per week for 4 week; n=6). The gene expression of NF-κB and TNF-α were analyzed in lung tissue by Real time–PCR. In order to determine the significant differences between groups independent t-test were used. Results:Aerobic exercise inhibited the gene expression of NF-κB and TNF-α. But there was no significant difference between A and B groups for TNF-α and NF-κB. Conclusion:We conclude that four week aerobic exercise decrease inflammatory status in lung tissue. Our results indicate a need for human studies that evaluate the lung responses to aerobic exercise.
【 授权许可】
Unknown
【 预 览 】
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