Drug Resistance of Acinetobacter in Selected Hospitals

Novelty in Biomedicine

Mansoureh Khalili Azad¹  Zahra Arab-Mazar¹  Sara Rahmati Roodsari¹  Latif Gachkar¹  Davood Yadegarynia¹ 

[1] Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran

关键词: Acinetobacter;    Drug Resistance;   

DOI  :  

学科分类：生物科学（综合）

来源: Shahid Beheshti University of Medical Sciences

【 摘 要 】

Background: Nowadays, nosocomial infection with multidrug-resistant Acinetobacter is an important problem in the world, which is facing wide spectrum antibiotics and hence has become resistant. Materials and Methods:In this study, positive cultures of Acinetobacter from one hundred clinical samples in seven hospitals from Tehran during 2012-2013 were collected for checking antibiotic susceptibility. Samples test with Ceftazidim, Cefepime, Amikacine and Imipenem by E-test and for Tazocin, Colistin and Tigecycline was performed with disk diffusion method. Results:For Colistin 10 samples, and for Tazocin, 40 samples were performed by E-test method. Thenboumanniispecies of bacteria and non- baumanniiAcinetobacter were separated by PCR and antibiotic susceptibility testing was performed on them. 89% of Acinetobacter samples wereboumanniispecies, which was isolated from respiratory secretions at ICU. Conclusion:Boumannii and non-boumannii species of bacteria with a high percentage were resistant to Ceftazidim, Amikacine, Cefepime, Tazocin and Imipenem. All baumannii and non-boumannii Acinetobacter were sensitive to Colistin, were only 75% sensitive to Tigecycline, which is a new glycylcycline. Colistin and Tazocin results in samples limited to the E-test method were similar with disk diffusion.

【 授权许可】

Unknown