Novelty in Biomedicine | |
Treatment of Recurrent Corneal Epithelial Defect by Autologous Serum Eye Drop | |
Kourosh Sheibani2  Ghazal Norouzi3  Hossein Mohammad Rabei1  | |
[1] Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran;Basir Eye Safety Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran;Shahid beheshti university of medical sciences | |
关键词: Autologous serum; cornea; epithelium; recurrent; | |
DOI : | |
学科分类:生物科学(综合) | |
来源: Shahid Beheshti University of Medical Sciences | |
【 摘 要 】
Background: The aim of the present study was to evaluate the efficacy of autologous serum eye drop in treatment of recurrent corneal epithelial defect. Materials and Methods:Fourteen patients with recurrent corneal epithelial defect were studied. Autologous serum was prepared from the patients and diluted in 20% normal saline. The patients were instructed to use the autologous serum every six hours. Patients were followed for a mean period of 18 months. Results:Four males (28.6%) and 10 females (71.4%) entered the study. Four patients stopped the treatment after three months with complete satisfaction from treatment. Patients reported a reduction in frequency and severity of attacks 4.6±2 weeks after the start of treatment. The mean number of attacks before the procedure was 7.6±0.9 per year which was reduced to 2.2±0.9 per year after treatment (p<0.001). The main side effects in patients were eye pruritus and redness which were well tolerated by patients. Conclusion:Autologous serum application seems to be a safe and effective method to treat recurrent corneal epithelial defect.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912010159724ZK.pdf | 324KB | download |