Effect of non-surgical periodontal treatment on transferrin serum levels in patients with chronic periodontitis

Journal of Dental Research, Dental Clinics, Dental Prospects

Fereshteh Naser Alavi¹  Ashkan Salari²  Masumeh Faramarzi³  Nazila Pashazadeh⁵  Adileh Shirmohammadi⁴  Mohamad Taghi Chitsazi⁴ 

[1] post-graduate student, department of operative dentistry, tabriz university of medical science, Tabriz, Iran;post-graduate student,department of periodontology,tabriz university of medical science,Tabriz,Iran;associated professor, department of periodontology,tabriz university of medical science,Tabriz,Iran;professor, department of periodontology,tabriz university of medical science,Tabriz,Iran;Nurse, department of periodontology,tabriz university of medical science,Tabriz,Iran

关键词: chronic periodontitis;    dental scaling;    inflammation;    root planning;    transferrin;   

DOI  :  

学科分类：农业科学（综合）

来源: Tabriz University of Medical Sciences * Faculty of Dentistry

【 摘 要 】

Background: Transferrin is a negative acute phase protein, which decreases during inflammation and infection. The aim of the present study was to evaluate changes in the transferrin serum levels subsequent to non-surgical treatment of chronic periodontal disease.Methods: Twenty patients with chronic periodontitis and 20 systemically healthy subjects without periodontal disease, who had referred to Tabriz Faculty of Dentistry, were selected. Transferrin serum levels and clinical periodontal parameters (pocket depth, clinical attachment level, gingival index, bleeding index and plaque index) were recorded at baseline and 3 months after non-surgical periodontal treatment. Data were analyzed with descriptive statistical methods (means ± standard deviations). Independent samples t-test was used to compare transferrin serum levels and clinical parameters between the test and control groups. Paired samples t-test was used in the test group for comparisons before and after treatment. Statistical significance was set at P<0.05.Results: The mean transferrin serum level in patients with chronic periodontitis (213.1±9.2 mg/dL) was significantly less than that in periodontally healthy subjects (307.8±11.7 mg/dL). Three months after periodontal treatment, the transferrin serum level increased significantly (298.3±7.6 mg/dL) and approached the levels in periodontally healthy subjects (P<0.05).Conclusion: The decrease and increase in transferrin serum levels with periodontal disease and periodontal treatment, respectively, indicated an inverse relationship between transferrin serum levels and chronic periodontitis.

【 授权许可】

Unknown