Polycarpol in Unonopsis, Bocageopsis and Onychopetalum Amazonian species: chemosystematical implications and antimicrobial evaluation

Revista Brasileira de Farmacognosia

Koolen, Hector H.F.¹  Souza, Antonia Q.L. de¹  Souza, Afonso D.L. de¹  Silva Filho, Francinaldo A. da¹  Pinheiro, Maria L.B.¹  Universidade Estadual de Campinas, Campinas, BR¹  Lima, Bruna R. de¹  Silva, Felipe M.A. da¹  Salvador, Marcos J.¹  Corrêa, Wallace R.¹  Almeida, Richardson A. de¹  Soares, Elzalina R.¹  Universidade Federal do Amazonas, Manaus, BR¹ 

关键词: Antimicrobial activity;    Bocageopsis;    Chemotaxonomic marker;    Onychopetalum;    Polycarpol;    Unonopsis;   

DOI  :  10.1016/j.bjp.2015.01.003

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Polycarpol, a recurrent lanostane-type triterpene in Annonaceae family, was confirmed by thin layer chromatography and mass spectrometry analysis in the aerial parts (twigs and trunk barks) of Unonopsis duckei R.E. Fr., U. floribunda Diels, U. rufescens(Baill.) R.E. Fr., U. stipitata Diels, Onychopetalum amazonicum R.E. Fr. and Bocageopsis pleiospermaMaas. Its chemotaxonomic significance was discussed for these three genera, as well for the Annonaceae family. In addition, the antimicrobial activity against several strains of microorganisms was evaluated for the first time for this compound, being observed significant antibacterial activity against Staphylococcus aureus (ATCC 6538), Staphylococcus epidermidis (ATCC 1228) and Escherichia coli (ATCC 10538 and ATCC 10799) with minimal inhibitory concentration values between 25 and 50 μg ml−1.

【 授权许可】

Unknown