Phytochemical researches and antimicrobial activity of Clinopodium nubigenum Kunth (Kuntze) raw extracts

Revista Brasileira de Farmacognosia

Negri, Riccardo¹  Guglielminetti, Maria¹  Morocho, Vladimir¹  Finzi, Paola Vita¹  Tosi, Solveig¹  Università degli Studi di Pavia, Italia¹  Vidari, Giovanni¹  Universidad Técnica Particular de Loja, Loja, Ecuador¹  Gilardoni, Gianluca¹  Malagon, Omar¹ 

关键词: antimicrobial activity;    Clinopodium nubigenum;    essential oil;    GC-MS;    1H-NMR;    13C-NMR;    schizonepetoside;    tipo de cerro;   

DOI  :  10.1590/S0102-695X2011005000139

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

The essential oil of the species Clinopodium nubigenum (Kunth) Kuntze, Lamiaceae, was analyzed by GC-MS and GC-FID, taking into account the more recent literature. Among the seventy compounds identified, the majority are oxygenated monoterpenoids. The essential oil, tested for antimicrobial activity, resulted effective in vitro against Candida albicans. From the aqueous MeOH extract of the aerial parts of the plant two nonvolatile compounds, named schizonepetoside A and schizonepedoside C, have been isolated. They are rare glycosyl terpenoids, which were previously isolated from only one plant, but never found before in the genus Clinopodium.

【 授权许可】

Unknown