Composição química volátil e não-volátil de Eupatorium ballotifolium Kunth, Asteraceae

Revista Brasileira de Farmacognosia

Braz-Filho, Raimundo¹  Santos, Hélcio S. dos¹  Albuquerque, Maria Rose Jane R.¹  Universidade Estadual do Ceará, Fortaleza, Brasil¹  Pessoa, Otília Deusdênia L.¹  Menezes, Jane Eire Silva A. de¹  Souza, Elnatan B. de¹  Universidade Estadual Vale do Acaraú, Sobral, Brasil¹  Faculdade de Educação de Itapipoca, Itapipoca, Brasil¹  Costa, Sônia Maria O.¹  Silva, Rochanne M. da¹  Universidade Federal do Ceará, Fortaleza, Brasil¹  Universidade Estadual do Norte Fluminense, Campos dos Goytacazes, Brasil¹ 

关键词: Eupatorium ballotifolium;    Asteraceae;    essential oil;    acetylcholinesterase activity.;   

DOI  :  10.1590/S0102-695X2010000400023

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

This work describes the chemical composition of the essential oils and the isolation of eleven substances from Eupatorium ballotifolium Kunth, Asteraceae. The essential oils were obtained by hydrodistillation, analyzed by GC/MS and evaluated towards the acetylcholinesterase enzyme. The oils yield was of 0.11% for the leaves and 0.03% for the stems. The main constituents of the oils were the sesquiterpenes β-caryophyllene (24.9 and 22.2%), spathulenol (17.7 and 12.4%) and epoxy-allo-aromadendrene (23.0 and 23.6%). From the hexane extract of the aerial part were isolated a mixture of sitosterol and stigmasterol, its glucosides, and the triterpenes taraxasteryl acetate and taraxasterol, while from the ethanol extract were obtained the flavonoids nepetin and 3-O-glucoside-quercetin. The triterpenes epi-friedelanol and dammara-20,24-dien-3β-ol were obtained from the hexane extract of roots, while the coumarin 11-hydroxy-11,12-di-hydroobliquine was obtained from the ethanol extract. The structures of all compounds were determinate based on spectroscopic methods such as IR, MS and 1H and 13C NMR

【 授权许可】

Unknown