In vitro cytotoxicity of extracts and fractions of Bursera tomentosa (Jacq.) Triana & Planch., Burseraceae, against human tumor cell

Revista Brasileira de Farmacognosia

Fundación Universitaria San Martín, Bogotá, Colombia¹  Castro, Clemencia de¹  Murcia, Tulia Riveros de¹  Alfonso, Alba N. Téllez¹  Pontificia Universidad Javeriana, Bogotá, Colombia¹  Rojas-Rozo, Ronald A.¹  Camargo, Jorge E. Robles¹ 

关键词: Cytotoxic activity;    Tumoral cellular lines;    Bursera tomentosa.;   

DOI  :  10.1590/S0102-695X2010000400019

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

To the extracts, fractions and subfractions obtained from leaves, flowers and bark of Bursera tomentosa (Jacq.) Triana & Planch., Burseraceae, its preliminary cytotoxic activity against to the cellular lines CSC-1595 and Colo 205 were evaluated, following the MTT method. The results showed that dichloromethane-methanol (9.5:0.5) subfraction obtained of ethyl acetate part from petroleum extract of leaves, like to display the bioactives substances with a strong cytotoxic activity, showing viability percentage of 3% and 15,3% to the concentration 30 µg/mL in human tumor cellular lines Colo 205 and CSC-1595 respectively.

【 授权许可】

Unknown