Sesquiterpenoids of Senecio bonariensis Hook. & Arn., Asteraceae

Revista Brasileira de Farmacognosia

Silva, Chana de Medeiros da¹  Alves, Sydney Hartz¹  Bolzan, Aline Abati¹  Pozzatti, Patrícia¹  Heinzmann, Berta Maria¹  Mallmann, Carlos Augusto¹  Universidade Federal de Santa Maria, Santa Maria, Brazil¹ 

关键词: Senecio bonariensis;    β-caryophyllene;    β-caryophyllene oxide;    germacrene D;    chemotaxonom y;    antimicrobial activity.;   

DOI  :  10.1590/S0102-695X2010000100018

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

From the leaves of Senecio bonariensis Hook. & Arn. three sesquiterpenoids were isolated. β-caryophyllene (1), β-caryophyllene oxide (2) and germacrene D (3) were characterized by GC-EI-MS, IR, 1H and 13C-NMR data. Their ecological and chemotaxonomical significance for the genus Senecio are discussed, as well as the biosynthetic correlation between the isolated substances. The antimicrobial activity of substances 1 and 2 were evaluated by the microdilution method against bacterial and fungal strains. Both compounds did not inhibit the microorganism growth at the tested concentrations.

【 授权许可】

Unknown