Inhibitory activity of aerial parts of Kalanchoe brasiliensis Cambess against microorganisms with variation profile antibiotic-resistant

Revista Brasileira de Farmacognosia

Pereira, Maria do Socorro V.¹  Siqueira-Júnior, José Pinto de¹  Souza, Ivone A. de¹  Universidade Federal da Paraíba, João Pessoa, Brasil¹  Universidade Federal de Pernambuco, Recife, Brasil¹  Silva, Jackeline G. da¹  Gurgel, Ana Pavla Diniz¹ 

关键词: Antimicrobial activity;    Kalanchoe brasiliensis;    Crassulaceae;    Staphylococcus aureus.;   

DOI  :  10.1590/S0102-695X2009000500024

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

This study reports the antimicrobial evaluation of the aerial parts of Kalanchoe brasiliensis Cambess, Crassulaceae, commonly used for the treatment of the oral mucosa inflammation, bronchitis and nasal congestion. The antimicrobial activity was assayed in petri dishes using the diffusion method for determination of the minimal inhibitory concentration (MIC) and the kill curve kinetic methods. It were used gram-positive and gram-negative strain, leveduriforms fungi strain classified in genus Cândida. Only the essential oil showed activity against methicilin resistant Staphylococcus aureus (MRSA). This action was considered bacteriostatic with the reduction to one log10 CFU/ml after six hour of exhibition at the concentration of 4% and 8%. There are studies accounts that polyphenols are present in the essential oil and are active against bacteria. K. brasiliensis is rich in polyphenols suggering that the antimicrobial effect showed is due to this. For this reason, the plant Kalanchoe brasiliensis, can represent a therapeutic alternative against infections caused for Staphylococcus aureus.

【 授权许可】

Unknown