Initial antimicrobial activity studies of plants of the riverside forests of the southern Uruguay River

Revista Brasileira de Farmacognosia

Vázquez, Alvaro¹  Cerdeiras, Maria Pia¹  Olivaro, Cristina¹  Ramos, Daniela¹  Silva, Pedro Almeida da¹  Fundação Universidade Federal do Rio Grande, Rio Grande, Brazil¹  Bertucci, Ana¹  Facultad de Química, Uruguay¹ 

关键词: Antimicrobial activity;    bioprospection;    Mycobacterium;    Candida.;   

DOI  :  10.1590/S0102-695X2009000100005

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Development of new antimicrobial compounds against different microorganisms is becoming critically important, as infectious diseases are still one of the leading causes of death in the world. Plants can be a useful source of these lead compounds. In this study, 66 extracts of 25 plants of the riverside forest of southern Uruguay River were studied for antimicrobial activity against Staphylococcus aureus, Listeria inocua, Escherichia coli, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Aspergillus niger and Candida albicans. Fifty-three of these extracts showed some kind of antimicrobial activity. Six of these (Eugenia mansoni, Eugenia repanda, Myrcianthes cisplatensis, Paullinia ellegans, Petunia sp and Ruprechtia laxiflora) presented activity against Mycobacterium tuberculosis with MIC values as low as 50 μg/mL.

【 授权许可】

Unknown