Natural products from plant origin potentially usefull in the asthma therapy

Revista Brasileira de Farmacognosia

Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil¹  Corrêa, Maria Fernanda P.¹  Instituto Nacional da Propriedade Industrial, Rio de Janeiro, Brasil¹  Costa, Sônia S.¹  Melo, Giany O. de¹ 

关键词: Asthma;    chronic inflammation;    Th2 cells;    medicinal plants;    natural products;    secondary metabolites.;   

DOI  :  10.1590/S0102-695X2008000500025

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Asthma is a chronic inflammatory disease, which represents a huge public health problem in developed and developing countries, has high death rates and elevated socioeconomic implications. The pathology is characterized by two different phases: the initial stage, mediated by acute inflammatory cell response and the late phase, responsible for specific immune cells. Currently, the main drugs used for asthma treatment are bronchodilator and anti-inflammatory agents, which mechanisms focus the relief of symptoms and attenuation of airway inflammation. However, therapies with those drugs have side effects besides they are not totally effective. Poor accessibility in the development countries and scarcity of safety drugs lead the search for new drugs to asthma treatment. Herbal natural products have elevated pharmacological potential against asthma, once they provide several molecules with specific mechanisms for the pathology control and treatment. Thus, search in herbal natural products plays an important role to find out specific and effective mechanisms.

【 授权许可】

Unknown