Bicyclogermacrene, resveratrol and fungitoxic activity on leaves extracts of Cissus verticillata L. Nicolson & Jarvis (Vitaceae)

Revista Brasileira de Farmacognosia

Moreno, Paulo R. H.¹  UNISA, São Paulo, Brasil¹  Oniki, Glaucia H.¹  Silva, Luciana da¹  Universidade de São Paulo, São Paulo, Brasil¹  Young, Maria Claudia M.¹  Agripino, Débora G.¹  Ladeira, Angela M.¹  Mayworm, Marco Aurélio S.¹  Instituto de Botânica, São Paulo, Brasil¹ 

关键词: Cissus verticillata;    Vitaceae;    fungitoxic activity;    sesquiterpene;    stilbene.;   

DOI  :  10.1590/S0102-695X2007000300010

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Cissus verticillata L. (Vitaceae) is popularly employed as hypoglicemic and it shows fungitoxic activity. This work aims at identification of fungitoxic compounds on extracts of leaves. The ethanol extract was partitioned using solvents of different polarities (hexane, chloroform, ethyl acetate and butanol) and its fungitoxic activity was analysed upon Cladosporium sphaerospermum. The chloroform and ethyl acetate extracts showed activity and they were fractionated by column chromatography and preparative TLC, respectively. Three terpenoids were isolated from the chloroform extract, one of them identified by GLC-MS analysis as sesquiterpene bicyclogermacrene. The active compound of the ethyl acetate extract was identified by HPLC analyses as stilbene resveratrol.

【 授权许可】

Unknown