Revista Brasileira de Farmacognosia | |
Fractionation of dichlorometane extract from Senecio desiderabilis Vellozo and evaluation of the antimicrobial activity | |
Camargo, Tarcisio de1  Deuschle, Régis A. N.1  Universidade Federal de Santa Maria, Santa Maria, Brasil1  Heizmann, Berta M.1  Mallmann, Carlos A.1  Alves, Sydney H.1  | |
关键词: Senecio desiderabilis; Asteraceae; antimicrobial activity; sesquiterpene; germacrene D.; | |
DOI : 10.1590/S0102-695X2007000200015 | |
来源: Sociedade Brasileira de Farmacognosia | |
【 摘 要 】
The present work describes the evaluation of the antimicrobial activity of a sesquiterpene fraction obtained from CH2Cl2 extract of Senecio desiderabilis Vellozo (Asteraceae), and of germacrene D isolated from it. The sesquiterpene fraction and the isolated substance were obtained by column chromatography and analysed by GC-MS. Substance identification was carried out by NMR. The antimicrobial activity was assayed by broth microdilution method, as preconized by NCCLS in the documents M27-A for yeasts and M7-A4 for bacteria. The sesquiterpene fraction showed moderated antimicrobial activity, and germacrene D did not inhibit the tested microorganisms.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO201912010144971ZK.pdf | 118KB | download |