Estudo químico de Zeyheria montana M. (bolsa‑de‑pastor)

Revista Brasileira de Farmacognosia

Universidade Federal de Minas Gerais¹  Wagner, H.¹  Jácome, R.L.R. P.¹  Raslan, D. S.¹  Universidade de Munique, Alemanha¹  Oliveira, A.B. de¹ 

关键词: Zeyheria montana;    Bignoniaceae;    naphtoquinones.;   

DOI  :  10.1590/S0102-695X2001000100002

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

Zeyheria montana M. (Bignoniaceae) is a widespread species in the Cerrado area of Minas Gerais, Brazil, and is popularly known as bolsa‑de‑pastor. In the Brazilian tradicional medicine its roots are used for the treatment of skin diseases. Several species of Bignoniaceae contain naphthoquinones, and lapachol was previously reported in the stem wood of Z. digitalis. This paper describes the isolation of three naphtoquinones from Z. montana stem barks, namely α‑lapachone, dehydro‑α‑lapachone and 4‑hydroxy‑α‑lapachone, besides lapachol, stearic acid and β‑sitosterol. Furthermore, we report the HPLC fingerprint for the species, which allowed the identification of the isolated compounds, except β‑sitosterol. Since the in vitro antimicrobial activity of lapachol and α‑lapachone has been previously described, the presence of these naphthoquinones in the roots of Z. montana corroborates its popular use for the treatment of skin diseases.

【 授权许可】

Unknown