Isolamento biomonitorado de alcalóides tóxicos de Prosopis juliflora (algaroba)

Revista Brasileira de Farmacognosia

Souza, J.C. de A.¹  Almeida, R.N.¹  Universidade Federal de Minas Gerais¹  Silva, M.S. da¹  Barbosa Filho, J.M.¹  Universidade Federal da Paraíba¹  Cunha, E.V.L. da¹  Pamplona, F.V.¹  Quintans-Júnior, L.J.¹  Tabosa, I.M.¹ 

关键词: Prosopis juliflora;    Leguminosae;    algaroba;    piperidine alkaloids;    juliprosopine;    juliprosine;    juliprosinene;    toxic activity.;   

DOI  :  10.1590/S0102-695X2000000100002

来源: Sociedade Brasileira de Farmacognosia

【 摘 要 】

A phytochemical investigation of the pods of Prosopis juliflora cultivated in the semi arid region of the State of Paraiba, monitored by pharmacological tests, led to the isolation, purification and identification of its main alkaloid - juliprosopine. The presence of other compounds such as juliprosine and juliprosinene, was observed through analysis of 13C NMR. This work suggests that the toxic activity, observed in laboratory animals, is chemicaly related with the piperidine alkaloids present in the pods of this Leguminosae.

【 授权许可】

Unknown