The antioxidant properties of solid-culture extracts of basidiomycetous fungi

The Journal of General and Applied Microbiology

Jeong-Do Kim¹  Beom Seok Kim¹  Jae-Jin Kim²  Byoung Jun Ahn³  Gyu-Hyeok Kim²  Joo-Hyun Hong²  Jaejung Lee² 

[1] Division of Biotechnology, Korea University;Division of Environmental Science & Ecological Engineering, Korea University;Division of Wood Chemistry & Microbiology, Korea Forest Research Institute

关键词: antioxidant;    basidiomycetes;    bioactive metabolites;    extracts;    radical-scavenging activity;   

DOI  :  10.2323/jgam.59.279

学科分类：微生物学和免疫学

来源: Applied Microbiology, Molecular and Cellulrar Biosciences Research Foundation

【 摘 要 】

Current studies of the antioxidant activity of fungal resources are mainly focused on the fruiting bodies of edible mushrooms. To access the potential of basidiomycetes in culture-state applications, extracts of solid cultures of 83 basidiomycetous fungi newly isolated from woody materials were prepared at the same concentration (10 mg/ml), and their antioxidant activities were measured using ABTS (2,2′-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid) and DPPH (2,2-diphenyl-1-picrylhydrazyl) radical-scavenging assays. Among the basidiomycetes tested, Cryptoporus volvatus, Daedalea dickinsii, Gloeophyllum abietinum, G. trabeum, Pseudomerulius curtisii and Stereum hirsutum exhibited good antioxidant activities. The EC50 value for the removal of free radicals was lowest (i.e., most effective) in the crude extract of S. sanguinolentum (19.61 g/ml), and reduced DNA damage based on a DNA nicking assay was observed for the extracts from the six basidiomycetous species above.

【 授权许可】

Unknown