Relationship between prognosis of papillary thyroid carcinoma patient and age: A retrospective single-institution study

Endocrine Journal

Yuuki Takamura¹  Akihiro Miya¹  Minoru Kihara¹  Yasuhiro Ito¹  Kaoru Kobayashi¹  Akira Miyauchi¹ 

[1] Department of Surgery, Kuma Hospital, Kobe 650-0011, Japan

关键词: Papillary thyroid carcinoma;    Prognosis;    Age;   

DOI  :  10.1507/endocrj.EJ12-0044

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(29)Cited-By(10)Age is an important prognostic factor in papillary thyroid carcinoma (PTC).In this study, we investigated the difference in prognosis of 7 subsets of PTC patients without distant metastasis at presentation or a history of radiation exposure (20 years or younger, 21-30 years, 31-40 years, 41-50 years, 51-60 years, 61-70 years, and older than 70 years).The lymph node recurrence rate was high in patients 20 years or younger and those older than 60 years.Distant recurrence and carcinoma death rates significantly elevated in patients older than 60 years.The incidence of significant extrathyroid extension markedly increased with age, although that of large node metastasis or extranodal tumor extension did not differ much among the 7 subsets.With the Kaplan-Meier method, lymph node recurrence rate was poor in patients 20 years or younger and in those older than 60 years.Poor distant recurrence-free and cause specific survivals of patients older than 60 years were identified in the series of PTC patients with and without these aggressive features.It is therefore suggested that 1) Lymph node recurrence rate was high in patients 20 years or younger and those older than 60 years and 2) prognosis, including distant recurrence-free survival and cause-specific survival, of patients older than 60 years was poor regardless of clinicopathological features of PTC at initial surgery.

【 授权许可】

Unknown