Desmin as a Possible Immunohistochemical Marker for Feline Hypertrophic Cardiomyopathy

Journal of Veterinary Medical Science

Yasuo NOMURA¹  Roslyn HAYMAN¹  Yumi UNE¹ 

[1] Department of Veterinary Pathology, School of Veterinary Medicine, Azabu University, 1-17-71 Fuchinobe, Sagamihara, Kanagawa 229-8501, Japan

关键词: desmin;    feline;    hypertrophic cardiomyopathy;   

DOI  :  10.1292/jvms.62.343

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(12)Desmin has been suggested as a possible histopathological marker for hypertrophic cardiomyopathy (HCM) in humans. To test whether a similar pattern of desmin staining applies to HCM in cats, we conducted an immunohistochemical study on myocardial samples from 13 cats (HCM 4, other cardiomyopathies (OCM) 4, and control 5). The pattern of staining for desmin in HCM cats was not the same as that reported in humans, but was weaker than in OCM cats and controls. This suggested that desmin may be a possible histochemical marker for feline HCM, but our data was insufficient to clearly confirm this.

【 授权许可】

Unknown