Serotypes, Antimicrobial Susceptibility, and Minimal Inhibitory Concentrations of Actionbacillus pleuropneumoniae Isolated from Slaughter Pigs in Taiwan (2002-2007)

Journal of Veterinary Medical Science

Chuen-Fu LIN¹  Chao-Nan LIN²  Tsung-Chou CHANG²  Cheng-Yao YANG³  Ming-Tang CHIOU² 

[1] Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology;Department of Veterinary Medicine, National Pingtung University of Science and Technology;Division of Animal Medicine, Animal Technology Institute Taiwan

关键词: Actinobacillus pleuropneumoniae;    antimicrobial susceptibility;    minimum inhibitory concentration;    erotype;    swine;   

DOI  :  10.1292/jvms.10-0339

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(15)Cited-By(2)In total, 211 isolates of A. pleuropneumoniae were collected from pigs with hemorrhagic pneumonia at slaughterhouses during 2002-2007. Serotypes, antimicrobial susceptibility and minimum inhibitory concentration (MIC) values were determined for each isolate of A. pleuropneumoniae to 10 antimicrobial agents. Serovar 1 of A. pleuropneumoniae was predominant in Taiwan in 138 of the 211 isolates, followed by serovars 2 and 5. More than 90% of collected isolates were sensitive to ceftiofur, cephalothin, and chloramphenical. However, lincospectin and gentamicin were relatively less susceptible with sensitivities of only 2.4 and 5.7%, respectively. Additionally, ceftiofur had the highest in vitro activity with an MIC50 of 2.2 μg/ml, followed by cephalothin (2.7 μg/ml) and chloramphenicol (7.9 μg/ml). Lincospectin had the least activity with MIC50 and MIC90 values of 73.9 and 114.5 μg/ml, respectively. The data indicate that ceftiofur and cephalothin were extremely active against A. pleuropneumoniae and with minimum MIC values. These drugs are suitable for controlling and treating hemorrhagic pleuropneumonia outbreaks in swine.

【 授权许可】

Unknown