Effect of Intramammary Injection of Nigella Sativa on Somatic Cell Count and Staphylococcus Aureus Count in Holstein Cows with S. aureus Subclinical Mastitis | Science Publications

American Journal of Animal and Veterinary Sciences

H. G. Azadi¹  A. Mohamadi¹  Z. Baghestani¹  N. Farzaneh¹  S.A. M. Shahri¹ 

关键词: Subclinical Mastitis;    Nigella sativa;    antimicrobial effects;    Mashhad;   

DOI  :  10.3844/ajavsp.2011.31.34

学科分类：兽医学

来源: Science Publications

【 摘 要 】

Problem statement: The seeds of Nigella sativa Linn. (Ranunculaceae) known as blackseed or black cumin, are used in herbal medicine all over the world for the treatment and prevention ofa number of diseases and conditions that include asthma, diarrhea and dyslipidaemia. Approach: Inthis study the effect of intramammary injection of Nigella Sativa Extract (NSE) in paraffin on quartermilk, quality and Somatic Cell Count (SCC) and the shedding pattern of Staphylococcus aureus wereinvestigated. Thirty Holstein cows, naturally infected with S. aureus subclinical mastitis, weresubjected to treatment with the NSE at a dose of 10 mL in paraffin (200 mg mL⁻¹) per day for 3 days,or with 10 mL paraffin as control. The injection areas were checked for adverse reactions. The dailymilk production was measured before and after treatment. Intramammary injection of NSE caused aremarkable healing. Quarter milk samples were collected for bacteriological analysis and Somatic CellCounts (SCC). The bacterial count moderately decreased in the treatment group. After the end of thetreatment, the numbers of S. aureus-infected quarters and milk SCC tended to decrease in the NSEtreatedcows. These clarifications were significantly higher one week post-treatment than pretreatment.Similar changes were not observed in the control group. Results: The results of the presentstudy showed that the NSE has potential as a therapeutic agent for S. aureus infection causingsubclinical mastitis of dairy cows and may contribute to the cow's recovery from mastitis. Conclusion:In conclusion, the results indicate that Nigella sativa might act as an antibacterial in vivo in dairy cows.

【 授权许可】

Unknown