Quantitative Studies of Nuclear Bodies in Astrocytes of Chicken Spinal Cord Following Axotomy

Journal of Veterinary Medical Science

Tomohiro IMAGAWA¹  Masato UEHARA¹  Hiroshi KITAGAWA¹ 

[1] Department of Veterinary Anatomy, Faculty of Agriculture, Tottori University

关键词: hyperactivation;    quantitative study;    ultrastructure;   

DOI  :  10.1292/jvms.60.773

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(21)The present study was designed to reveal whether astrocytic activation following axotomy causes a numerical increase of nuclear bodies (NBs) in chicken astrocytes. Astrocytes in the spinal cord were activated by a unilateral spinal nerve transection. The frequency of NBs was calculated at the lateral motor columns of the normal group and at the ipsi- and contralateral sides of operated group. In the growing chickens, NBs of each astrocyte were a few and decreased steadily in number with age. In the operated chickens, the frequency of NBs elevated temporarily both in the ipsi- and contralateral sides, and reached its maximum value by 30 post-operative days. The frequency of NBs increased more prominently in the operated side than in the unoperated side. Thus, the present study provides the first evidence for a significant increase in the number of NBs in the hyperactive astrocytes caused by axotomy.

【 授权许可】

Unknown