Consecutive Intake of Fermented Milk Containing Bifidobacterium breve Strain Yakult and Galacto-oligosaccharides Benefits Skin Condition in Healthy Adult Women

Bioscience of Microbiota, Food and Health

Kouji MIYAZAKI²  Saho SUGIMOTO²  Chiaki KAGA²  Chiaki NONAKA¹  Ryoko IIZUKA²  Toshiro SONE²  Kazutoshi OEDA¹  Mitsuyoshi KANO²  Fumiyasu ISHIKAWA²  Katsuyuki MANABE²  Norie MASUOKA² 

[1] Faculty of Research and Development, Yakult Honsha;Yakult Central Institute for Microbiological Research

关键词: phenol;    prebiotics;    probiotics;    skin condition;    Bifidobacterium;    galacto oligosaccharides;    skin hydration;   

DOI  :  10.12938/bmfh.32.33

学科分类：生物科学（综合）

来源: Nihon Bifizusukin Senta / Japan Bifidus Foundation

【 摘 要 】

References(28)Cited-By(6)A double-blind, placebo-controlled, randomized trial was conducted to investigate the beneficial effect of probiotic and prebiotic fermented milk on the skin of healthy adult women. Forty healthy Japanese adult female volunteers with healthy skin randomly received either a bottle of probiotic and prebiotic fermented milk containing Bifidobacterium breve strain Yakult and galacto-oligosaccharides (GOS) (active group) or a non-fermented placebo milk containing neither probiotics nor GOS (placebo group) daily for 4 weeks. Before and after intake, hydration levels and cathepsin L-like activity in the stratum corneum and phenol levels in the serum and urine were determined. After intake, the hydration level of the stratum corneum decreased significantly in only the placebo group and was significantly lower than in the active group (p=0.031). Cathepsin L-like activity, an indicator of keratinocyte differentiation, was significantly increased in the active group (p=0.027). Serum and urine phenol levels decreased significantly in the active group (p=0.014, p=0.002, respectively), and serum phenol levels were significantly lower in the active group compared with the placebo group (p=0.006). The consecutive intake of probiotic and prebiotic fermented milk can benefit skin condition without dryness and decrease the levels of phenol production by gut bacteria in healthy adult women.

【 授权许可】

Unknown