期刊论文详细信息
Public Health Nutrition | |
Reproducibility and validity of an FFQ to assess usual intake of methyl-group donors | |
Greet Vansant1  Gudrun Koppen1  Ine Doperé1  Inge Huybrechts1  Lode Godderis1  Sara Pauwels1  | |
关键词: FFQ; Dietary assessment; Validation; Methyl-group donors; | |
DOI : 10.1017/S1368980014003140 | |
学科分类:卫生学 | |
来源: Cambridge University Press | |
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【 摘 要 】
AbstractObjectiveTo develop and validate a novel FFQ to assess the daily intake of four methyl-group donors (methionine, choline, betaine and folate).DesignThe relative validity of the FFQ was assessed by comparison with 7 d estimated diet records (n 80) and its reproducibility was evaluated by repeated administrations 6 weeks apart (n 92). Paired Student t tests were used to compare group means and de-attenuated intra-class correlations to investigate the ability of the FFQ to rank individuals according to their methyl-group donor intake. De-attenuated intra-class correlation coefficients were calculated between the test and reference method for methionine, choline, betaine, folate and the sum of methyl-group donors. The weighted kappa (κw) was calculated as a measure of tertile agreement.SettingFlanders, Belgium.SubjectsThe FFQ was validated among Flemish women of reproductive age (18–35 years).ResultsThe questionnaire had an acceptable ranking ability (r=0·32–0·68; κw=0·10–0·35), but overestimated the daily intake of folate (280·6 μg v. 212·0 μg) and betaine (179·1 mg v. 147·0 mg) compared with the 7 d estimated diet record. Cross-classification analysis indicated that 20 % (choline) of the participants were grossly misclassified in the validation study. The correlation between repeated administrations was good (r=0·62–0·83) with a maximal misclassification of 7 % for betaine (κw=0·44–0·66).ConclusionsThese results indicate that this newly developed FFQ is a reliable instrument with acceptable validity for ranking individuals according to methyl-group donor intake (except for a poor agreement for choline (κw=0·10) and a fair ranking ability for betaine (r=0·32)) in Flemish women of reproductive age.【 授权许可】
Unknown
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