Occurrence of Cerebrocortical Necrosis in A Goat in Okinawa Prefecture, Japan

Journal of Veterinary Medical Science

Tomotaka ARAKAKI³  Shusaku SHIMOJI⁴  Tomomi OZAWA¹  Masanao MATAYOSHI⁴  Tsutomu UCHIHARA²  Miho ARAKI²  Osamu TSUHA⁴ 

[1] National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), 3–1–5 Kannondai, Tsukuba, Ibaraki 305–0856, Japan;Okinawa Prefectural Institute of Animal Health, 112 Kohagura, Naha, Okinawa 900–0024, Japan;Central Veterinary Clinic Center NOSAI-Okinawa, 2352–1 Inamine, Oozato, Nanjyo, Okinawa 901–1204, Japan;Okinawa Prefecture Central Livestock Hygiene Service Center, 2505 Oozato, Oozato, Nanjyo, Okinawa 901–1202, Japan

关键词: cerebrocortical necrosis;    goat;    thiamine;   

DOI  :  10.1292/jvms.12-0009

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(13)A 6-month-old male Nubian goat suddenly showed dullness, tachypnea, recumbency and opisthotonus in August 2011 in Okinawa, Japan. The goat was consequently necropsied: gross lesions in the brain included slightly swollen foci of yellowish discoloration on the cerebral hemisphere. Histopathologically, necrosis of the cortex with ischemic changes of neuronal cells was present, and swelling of the vascular endothelium, thickening of the basement membrane and diffuse infiltration of macrophages were observed in the cerebral lesion. Autofluorescence of the cerebral cortex was confirmed by an ultraviolet light test. The thiamine levels of the blood serum and tissue samples (brain, liver and heart) of the goat were low compared with goats from the same herd. The goat was diagnosed with cerebrocortical necrosis (CCN). This is the first case report of caprine CCN in Japan.

【 授权许可】

Unknown