Comparative Studies on Distribution and Fine Morphology of the Intestinal Peyer's Patches in Mongolian Gerbils (Meriones unguiculatus) and Mice

Journal of Veterinary Medical Science

Haruko IKI¹  Kosaku FUJIWARA¹  Mio OHMURA¹  Shigeki TSUTSUI¹  Satoshi KOMAZAWA¹ 

关键词: follicle-associated epithelium (FAE);    M cell;    Mongolian gerbil;    mouse;    Peyer's patch;   

DOI  :  10.1292/jvms.53.899

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(27)Cited-By(2)The intestinal Peyer's patches (PP) were significantly different in distribution and fine morphology between Mongolian gerbils and mice. The PP of gerbils were evenly distributed from the duodenum to ileum, whereas the PP of mice were more densely distributed in the lower ileum than other parts of the intestine. In gerbils, each PP had a much greater number of lymphoid follicles than in mice, although the total number of PP was smaller. Electron microscopy revealed that the PP dome of gerbils was covered with two types of epithelial cells, one with shorter microvilli and the other with longer ones, whereas the epithelial cells of the murine PP dome was uniform-shaped with numerous medium-sized microvilli. Some dome absorptive cells of gerbils were morphologically similar to poorly differentiated crypt cells of mice, suggesting to be immature M cells.

【 授权许可】

Unknown