Seminoma in a koi carp Cyprinus carpio: histopathological and immunohistochemical findings

Diseases of Aquatic Organisms

Barbara Brunetti¹  Rubina Sirri¹  Heike Schmidt-Posthaus¹  Giuseppe Sarli¹  Luciana Mandrioli¹  Barbara Bacci¹  Valeria Grieco¹ 

关键词: Seminoma;    Koi carp;    Histology;    Immunohistochemistry;   

DOI  :  10.3354/dao02273

学科分类：生物科学（综合）

来源: Inter-Research

【 摘 要 】

ABSTRACT: A spontaneous seminoma in a 3 yr old male koi carp Cyprinus carpio L. is described. The animal, presenting a symmetric abdominal enlargement, showed a celomatic multinodular, white-yellowish and firm mass that infiltrated the liver and the intestine wall. Histologically, the neoplasm was non-encapsulated and poorly demarcated, showed invasive growth and was characterized by a lobular architecture, subdivided by abundant fibro-connective septa. Large necrotic and calcified areas together with small aggregates of residual spermatids were present. We diagnosed a classical seminoma with a diffuse pattern. Neoplastic cells cross-reacted with vimentin, placental alkaline phosphatase, and c-KIT. An immunohistochemical phenotypization of the tumor was performed to exclude other celomatic neoplasms and to compare this seminoma with those reported in mammals and humans.

【 授权许可】

Unknown