Evaluation of Urinary Enzymes in Dogs with Early Renal Disorder

Journal of Veterinary Medical Science

Mitsugi TAKAHASHI¹  Haruko TERUI¹  Ryoukichi ISHIKAWA¹  Masami UECHI¹  Yusuke NOGAMI¹  Tomohiro NAKAYAMA¹  Yoshito WAKAO¹ 

关键词: heartworm disease;    renal failure;    urinary enzyme;   

DOI  :  10.1292/jvms.56.555

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(14)Cited-By(12)We investigated urinary N-acetyl-β-D-glucosaminidase NAG (EC 3.2.1.30), γ-glutamyl transpeptidase γ-GTP (EC 2.3.2.2) and glycyl-prolyl dipeptidyl aminopeptidase GP-DAP (EC 3.4.14.5) in dogs with heartworm disease and renal failure. In the renal failure dogs, the NAG, γ-GTP and GP-DAP index were significantly higher than those in the healthy dogs. In the heartworm disease dogs with normal chest X-rays (HW I), none of the enzyme values was significantly different from those of the healthy controls. In the dogs with heartworm disease showing abnormal heart shadows on their chest X-rays (HW II), enzyme values were significantly higher than those in the healthy dogs (P<0.01) and the HW I dogs (P<0.01). Thus, these urinary enzymes tests are available for the early detection of renal disorders.

【 授权许可】

Unknown