Morning Granulocytopenia in a Case of Graves' Disease

Endocrine Journal

SHIGENORI NAKAMURA¹  MAKO ISAJI¹  MASATOSHI ISHIMORI¹ 

[1] Department of Internal Medicine, Gifu Red Cross Hospital

关键词: Graves' disease;    Granulocyte colony-stimulating factor;    Cortisol;    Diurnal change;   

DOI  :  10.1507/endocrj.48.181

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(8)Cited-By(1)A 65-year-old woman with Graves' disease presented marked diurnal changes in white blood cell (WBC) and granulocyte counts. Granulocyte count was low and sometimes decreased to 0.2-0.3×109/l in the early morning and increased in the afternoon irrespective of her thyroid status. She did not develop sore throat or fever during the investigation period. The present study indicates that these unusual diurnal changes in WBC and granulocyte counts should be considered in the differential diagnosis of agranulocytosis in Graves' disease patients treated with an antithyroid drug.

【 授权许可】

Unknown