Association of Oral Contraceptives and Abnormal Pap Smear | Science Publications

American Journal of Applied Sciences

Mohammad A. Ramezani¹  Mohammadreza Hassany¹  Sayedmohsen Sayednozadi¹ 

关键词: Oral Contraceptives (OCs);    cervical dysplasia;    pap smear;    mashad;    iran;   

DOI  :  10.3844/ajassp.2005.1150.1152

学科分类：自然科学（综合）

来源: Science Publications

【 摘 要 】

To assess the hypothesis that combined Oral Contraceptive (OCs) increase the risk of cervical neoplasia, we conducted a multicenter Case-Control study in Mashhad, the capital of Khorasan province. Seventy-eight women with moderate to severe dysplasia at Pap smear as case group and one hundred fifty nine women with normal Pap smear were selected as the control group for evaluation. The both case and control groups were matched by age, parity and socioeconomic status. All of the women in this study were single partner as husband and no smoker. 30 percent of cases and 64.8 percent of controls were used OCs. The duration of OCs use was the same in both. The odds ratio for OCs consumption was 0.2 with 95% confidence interval 0.11-0.4 in Logistic regression analysis. In contrast to some other studies, our findings showed an association between OCs and cervical dysplasia and there was a protective effect of OCs for cervical dysplasia.

【 授权许可】

Unknown