Neonatal Purpura Fulminans

Journal of Nepal Paediatric Society

J Yadav¹  D Sharma¹ 

[1] Department of Paediatrics, Pt.B.D.S PGIMS Rohtak, Haryana

关键词: Neonatal purpura fulminans;    skin necrosis;    disseminated intravascular coagulation.;   

DOI  :  

学科分类：儿科学

来源: Nepal Paediatric Society

【 摘 要 】

Neonatal purpura fulminans is a rare, life-threatening condition of dermal microvascular thrombosis associated with DIC and perivascular hemorrhage in the newborn period associated with high morbidity and mortality [1]. Gram negative organisms and Staphylococcus species are the most common causes of the acute infectious type [2]. It may be congenital, as a result of protein C and S deficiency, or acquired due to severe infection. It is characterized by the rapid spread of symmetrical, bluish-black hemorrhages into the skin, affecting mainly the extensor surfaces of the extremities and showing a tendency to deep necrosis and the formation of sero-sanguineous bullae. The haemorrhagic areas are well defined and are surrounded by oedema. These lesions are accompanied by a high fever and intense systemic symptoms.

【 授权许可】

Unknown