Specific fatty acids as metabolic modulators in the dairy cow

Revista Brasileira de Zootecnia

Grummer, R.R.¹  Pires, J.A.A.¹ 

[1] University of Wisconsin, Madison, USA

关键词: bovine;    CLA;    linseed;    fish oil;    metabolism;    polyunsaturated fatty acid     Introduction Lactation performance of dairy cows depends to a large extent on their ability to cope with metabolic demands of the periparturient period;   

DOI  :  10.1590/S1516-35982008001300033

学科分类：兽医学

来源: Universidade Federal de Vicosa

【 摘 要 】

This review summarizes recent developments on the utilization of specific fatty acids to modulate bovine energy metabolism, with emphasis on the periparturient dairy cow. A number of experiments have assessed the effects of polyunsaturated fatty acids on bovine hepatic energy metabolism using in vitro and in vivo models. Treatment of hepatocytes with specific fatty acids altered energy metabolism in vitro. For example, linolenic acid seemed to decrease hepatocyte triacylglycerol accumulation. This effect was confirmed in vivo, using parenteral infusions of emulsions derived from different fat sources to feed-restricted non-lactating cows. Additionally, polyunsaturated fatty acids can increase whole body response to insulin, potentially enhancing antilipolytic effects of insulin and muscle protein anabolism in the bovine. There is limited literature on the effects of feeding fat sources rich in omega-3 polyunsaturated fatty acids, such as fish oil and linseed oil, on metabolism of periparturient dairy cows. Available research has yielded conflicting results which need further clarification. On the other hand, specific isomers of conjugated linoleic acid consistently induce milk fat depression and are able to decrease energy export in milk by periparturient dairy cows. Nonetheless, research is still needed to assess whether these effects will ultimately benefit productivity and health status of periparturient dairy cows. Limitations of available methods to protect fatty acids from ruminal biohydrogenation are also addressed.

【 授权许可】

CC BY-NC