Histopathological Comparison of Pulmonary Artery Lesions Between Raccoon Dogs (Nyctereutes procyonoides) and Domestic Dogs Experimentally Infected with Dirofilaria immitis

Journal of Veterinary Medical Science

Kazuhide NAKAGAKI¹  Motonobu YOSHIDA³  Atsushi KAWABATA²  Kinji SHIROTA² 

[1] Laboratory of Wildlife Medicine, Nippon Jui-Seimeikagaku University;Research Institute of Biosciences, Azabu University;Research Institute of Animal Science, Dainippon Pharmaceuticals Ltd.

关键词: Dirofilaria immitis;    raccoon dog;    villous endarteritis;   

DOI  :  10.1292/jvms.70.301

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(14)Cited-By(2)Five raccoon dogs (Nyctereutes procyonoides) and two domestic dogs (Canis familiaris) were subcutaneously infected with 100 infective larvae (L3) of Dirofilaria immitis. Two and five worms, respectively, were collected from two of three raccoon dogs. Villous endarteritis was found in the raccoon dog with five worms and two dogs at 116 days after infection. The number of recovered worms in the raccoon dogs was significantly smaller than that of the domestic dogs having 22 and 29 worms, while histopathological features and the severity of the lesions in the raccoon dogs were similar to those in the domestic dogs. The vascular lesions in two chronically-infected raccoon dogs turned into much severe at 565 and 590 days after inoculation.

【 授权许可】

Unknown