Proto-Oncogene of Genomic DNA, Related to the Human Epidermal Growth Factor Receptor (EGFR) Gene, from Clinically Normal Domestic Animals

Journal of Veterinary Medical Science

Kazuyuki UCHIDA¹  Ryoji YAMAGUCHI¹  Mina ROSTAMI¹  Noriyuki MIYOSHI¹  Susumu TATEYAMA¹  Kiyonori KAI¹ 

关键词: epidermal growth factor receptor gene;    hybridization;    proto-oncogene;   

DOI  :  10.1292/jvms.55.319

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(10)Cited-By(2)Genomic DNAs of cattle, horses, pigs, dogs, cats and chickens were surveyed using Southern blot hybridization analysis, with a human EGFR cDNA fragment. Several bands with different numbers and molecular weights were observed under the condition of low stringency in the individual animal species. The bands showing DNA polymorphism were observed among bovine genomic PstI-digested DNAs from 4 individuals and EcoRI-digested genomic DNAs from 4 chickens. These results may provide basic data which are useful for analysis of tumorigenetic mechanisms in domestic animals.

【 授权许可】

Unknown