Infectious Spondylitis in a Patient with Chronic Kidney Disease: Identification of Campylobacter fetus Subsp. testudinum by 16S Ribosomal RNA Sequencing

Japanese Journal of Infectious Diseases

Sung Un Shin¹  Eun Hui Bae¹  Hong Sang Choi¹  Seong Kwon Ma¹  Soo Wan Kim¹ 

[1] Department of Internal Medicine, Chonnam National University Medical School

关键词: spondylitis;    bacteremia;    Campylobacter fetus;    rRNA gene sequencing;   

DOI  :  10.7883/yoken.JJID.2015.461

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

References(11)Cited-By(1)We report the first case of spondylitis with bacteremia caused by Campylobacter fetus subsp. testudinum identified by 16S ribosomal ribonucleic acid (rRNA) gene sequencing. An 81-year-old man presented with fever and general weakness. His medical history included end-stage renal disease, hypertension, and type 2 diabetes. Despite empirical antibiotic treatment, his fever and back pain persisted. Magnetic resonance imaging with gadolinium enhancement showed a low-signal-intensity lesion in T1-weighted imaging and a high-signal-intensity lesion in T2-weighted imaging at the L3 vertebral body. C. fetus grew on 1 pair of blood cultures. C. fetus subsp. testudinum was identified via 16S rRNA sequencing of the cultivated organisms. The patient recovered uneventfully after 6 weeks of optimal antibiotic treatment, selected using susceptibility tests. C. fetus spondylitis is a very rare disease. In this unique case involving end-stage renal disease, the underlying pathogen was identified by 16S rRNA sequencing.

【 授权许可】

Unknown