The relationship between serum thyrotropin and components of metabolic syndrome

Endocrine Journal

Beibei Wang²  Jiani Wang²  Haibo Xue²  Qian Xing²  Xin Hou²  Mengchun Li²  Chenyan Li¹  He Liu²  Yanyan Chen²  Sen Wang²  Zhongyan Shan¹  Fengwei Jiang²  Jiashu Yu²  Li Lu²  Liangfeng Shi²  Ningna Li²  Xue Bai²  Yaxin Lai¹  Lin Zhu²  Weiping Teng²  Xiaochun Teng¹ 

[1] Department of Endocrinology and Metabolism, The First Hospital of China Medical University, Shenyang, China;The Endocrine Institute of China Medical University, The Liaoning Provincial Key Laboratory of Endocrine Diseases, Shenyang, China

关键词: Metabolic syndrome;    Thyrotropin;    Subclinical hypothyroidism;    Subclinical hyperthyroidism;   

DOI  :  10.1507/endocrj.K10E-272

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(31)Cited-By(34)To explore the relationship between serum thyrotropin and components of metabolic syndrome in a Chinese cohort.A total of 1534 adult inhabitants in DaDong district of Shenyang were asked to fulfill the questionnaire, complete physical examination and OGTT.Blood samples were collected to test thyrotropin (TSH), fasting plasma glucose (FPG), OGTT 2h PG, fasting insulin (FINS), triglyceride (TG) and high density lipoprotein cholesterol (HDL-C).Serum TSH in metabolic syndrome group was higher than that in the non-metabolic syndrome group (2.54 mIU/L vs. 2.22 mIU/L, p‹0.05).TG level increased significantly in subclinical hypothyroid group compared with euthyroid subjects (1.73±0.12 mmol/L vs. 1.47±0.03 mmol/L, p‹0.05), and HDL-C decreased significantly in patients with subclinical hypothyroidism compared with euthyroid subjects (1.26±0.27 mmol/L vs. 1.33±0.27 mmol/L, p‹0.05).The prevalence of hypertension was higher in the subclinical hypothyroid group than that in euthyroid group (42.86% vs. 33.2%, p‹0.05).The serum TSH within the reference range was positively related with the prevalence of overweight/obesity.Slight increase in serum TSH maybe a risk factor for metabolic syndrome.

【 授权许可】

Unknown