Serum Growth Hormone and Insulin-Like Growth Factor-1 Concentrations in Japanese Black Cattle with Renal Tubular Dysplasia

Journal of Veterinary Medical Science

Masaki TAKASU²  Naohito NISHII²  Hitoshi KITAGAWA²  Katsuya KITOH²  Yasunori OHBA²  Yoshihide SASAKI²  Kazuo KATOH¹ 

[1] Department of Animal Physiology, Graduate School of Tohoku University;Laboratory of Veterinary Internal Medicine, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University

关键词: growth hormone;    growth retardation;    IGF-1;    Japanese black cattle;    renal tubular dysplasia;   

DOI  :  10.1292/jvms.67.399

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(25)Cited-By(2)To elucidate the cause of growth retardation, 14 cattle with renal tubular dysplasia (RTD) were investigated by determining serum growth hormone (GH) and insulin-like growth factor (IGF)-1 concentrations. Compared with 6 healthy cattle, the baseline, maximum, area under the curve and peak amplitude of serum GH concentrations were higher or tended to be higher. Serum IGF-1 concentrations were lower normal or lower in cattle with RTD than in healthy cattle. Serum IGF-1 concentrations correlated significantly with body weight and chest girth, but not with serum GH and creatinine concentrations. Growth retardation in RTD might be associated partially with GH resistance.

【 授权许可】

Unknown