Evaluation of the in vitro cell-material interactions and in vivo osteo-integration of a spinal acrylic bone cement

European Spine Journal

Mauro Alini¹  Antoine Alves¹  Sophie Verrier¹  Marianna Peroglio¹  Andreas Boger¹  Lisa Hughes¹ 

[1] AO Research Institute, Clavadelerstrasse 8, 7270 Davos Platz, Switzerland

关键词: Acrylic bone cement;    Osteo-integration;    In vitro;    In vivo implantation study;    Bone marrow mesenchymal stem cells;   

DOI  :  10.1007/s00586-011-1945-9

学科分类：骨科学

来源: Springer

【 摘 要 】

Polymethylmethacrylate bone cements have proven performance in arthroplasty and represent a common bone filler, e.g. in vertebroplasty. However, acrylic cements are still subject to controversy concerning their exothermic reaction and osteo-integration potential. Therefore, we submitted a highly filled acrylic cement to a systematic investigation on the cell-material and tissue-implant response in vitro and in vivo.

【 授权许可】

Unknown