Increased proportions of CCR4+ cells among peripheral bloodCD4+ cells and serum levels of allergen-specific IgE antibody in caninechronic rhinitis and bronchitis

Journal of Veterinary Medical Science

Toshihiro WATARI¹  Yoshiki YAMAYA¹ 

[1] Laboratory of Comprehensive Veterinary Clinical Studies, Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Kameino 1866, Fujisawa, Kanagawa 252-0880, Japan

关键词: bronchitis;    canine;    rhinitis;   

DOI  :  10.1292/jvms.14-0338

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(26)Canine chronic rhinitis (CR) and bronchitis (CB) are suspected to be allergic diseases.The present study tested whether dogs diagnosed with CR or CB present an atopicpredisposition based on the ratio of CC chemokine receptor 4 (CCR4)-positive cells amongperipheral blood CD4-positive cells (CCR4/CD4) and the serum levels of allergen-specificIgE antibodies. We found that most dogs with CR and CB have a possibility of atopicpredisposition, and macrolide therapy constitutes an alternative to corticosteroid therapyin controlling the clinical signs.

【 授权许可】

Unknown